Can a single bad LOR ruin my chances of a college admit?

I am dealing with one very mercurial professor and I had a bit of a incident with him. I think I might have offended him slightly(I told him about the deadline to submit LOR in a nicest possible way and yet he flared up on me). My seniors tell me that he is prone to extract grudges on people who ask him for LOR. I am afraid I might have offended him, he kinda scares me. But he is a very good researcher in Computer Networks and I performed well in his class. I don't want to drop him and choose another faculty.

Now I know very well that the other two lecturers are going to rate me good but if this lecturer gives me a bad rating will it harm my chances of getting a admit?