Consequences of applying for two (or more) programs in one university

Is it alright to apply for two different programs in one university (and in some cases programs within one department) at the same time?

I wonder whether that would affect the decision of the admission committee. For instance, will that make them reject both applications due to the differences (different ideas expressed) in each statement of purpose? Will it have any effect in general?

Finally, do you recommend such approach?