How to select a publishing venue for an interdisciplinary research?

I am curious to hear some words of advice on how to select a publishing community for a multidisciplinary topics.

Your contribution is that methods in area A, which is your main area, can solve problems in B more efficiently than traditionally used methods from area C.

Where do you publish, A, B, or C? You are contributing a new application domain to your main area A along with theory that supports the bridge between A and B, but your reviewers are not familiar with domain B and do not find it relevant. You are contributing new tools to the problem domain B. Yet, all related work in C.

This is CS research, if that helps.